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ANDRAL Gabriel. Essai d'hématologie pathologique.. Paris, Fortin, Masson et Cie, 1843, 1843.

Price: US$445.49 + shipping

Condition: Near Fine

Description: Paris, 1843; 1 vol. in-8 (22 x 14 cm), (4), 186 pp., 32 pp. (catalogue des livres de fonds de Fortin, Masson et Cie, février 1843), exemplaire dans sa brochure d'origine, non coupé à partir de la page 5; rousseurs pâles éparses (comme souvent), bon état. Edition originale de la première monographie scientifique consacrée à l'hématologie et de l'un des ouvrages importants dans l'histoire de cette spécialité. THE BIRTH OF SCIENTIFIC HEMATOLOGY (UNCUT AND UNTRIMMED COPY AS ISSUED, IN THE ORIGINAL PRINTED WRAPPERS). Cette monographie fut traduite et publiée en anglais dès l'année suivante. Gabriel Andral (1797-1876), professeur de pathologie médicale à la Faculté de médecine de Paris, étudie le sang sur le plan chimique, physique et microscopique. Il analyse différents constituants (fibrine, albumine), en essayant de définir leurs valeurs normales et de préciser leurs variations dans diverses affections. Il cherche à classer les maladies en en trois groupes : celles avec des proportions anormales de constituants sanguins normaux, celles qui présentent des modifications sanguines qualitatives (volume ou forme des cellules), et celles renfermant des substances n'existant pas dans le sang normal. Il décrit clairement diverses affections (polycythémie, pseudopolyglobulie de stress ou syndrome de Gaisböck, septicémie) et reconnait plusieurs formes d'anémie (saturnine ). REFERENCES : Garrison & Morton, 3060: "The first monograph on haematology. Andral established analysis of the blood on the basis of exact knowledge of the blood components. He analysed the blood fibrin and albumin. He recognized several forms of anaemia, including that due to lead poisoning."; Wintrobe MM: Blood, pure and eloquent, pp. 17-19, 607-608, 635; Uthman E: Understanding Anemia, p. 4: "At the time of the publication of the first textbook of hematology by the French physician Gabriel Andral in 1843, there was no appreciation for the basic concept held today that clinical anemia is due to inadequate numbers of red blood cells."; Surgenor D: The Red Blood Cell, vol. 1, p. 7: "The “Essay in Pathological Hematology,” published in 1843, is a memorable step in the development of hematology. In this paper, Andral (1843) attempted to establish standard values for the components of blood. A noteworthy beginning was also made to classify diseases in which blood changes occur into three groups: those with abnormal proportions of normal blood constituents, those with qualitative changes in the blood (volume or form of the cells), and those with substances which do not exist in normal blood."; Long A: Selected readings in pathology, pp. 247-253; Russell RP & Conley CL: Benign Polycythemia: Gaisböck's Syndrome, Arch Intern Med, 1964, 114(6), 734-740; Dreyfus C: Gabriel Andral (1797-1876). Un hématologue de la première moitié du XIXe siècle, Nouv Rev Fr Hematol, 1963, 3, 261-76; Teyssou R : Gabriel Andral, pionnier de l'hématologie; Heirs of Hippocrates, 1583.

Seller: Jean-Pierre AUBERT, Quiberon, France

ANDRAL, Gabriel. Essai d'hématologie pathologique.. Paris: Fortin, Masson, 1843., 1843.

Price: US$450.00 + shipping

Condition: Very Good

Description: 2 leaves, 186 pp. Contemporary 1/4-leather and marbled boards. Light stain in lower corner of last 30 leaves. Foxed. Very Good. First Edition. Garrison-Morton 3060: "The first monograph on hematology. Andral established analysis of the blood on the basis of exact knowledge of the blood components. He analysed the blood fibrin and albumin." "Here Andral first uses the terms anemia and hyperemia and clearly describes a number of diseases of the blood including lead poisoning, septicemia, and polycythemia" (Heirs of Hippocrates 1583).

Seller: Scientia Books, ABAA ILAB, Arlington, MA, U.S.A.

Andral, Gabriel. Essai d'hématologie pathologique.. , 1843.

Price: US$735.06 + shipping

Description: Paris, Fortin, Masson et Cie., 1843, 8°, (4), 186 pp., feiner Halbledereinband; etwas fleckig; mit ExLibris "Herbert McLean Evans / Library of Medical Classics". First Edition! "The first monograph on haematology. Andral established analysis of the blood on the basis of exact knowledge of the blood components. He analysed the blood fibrin and albumin. He recognized several forms of anaemia, including that due to poisoning." "This short volume is one of the most important works in the history of haematology. Here Andral first uses the terms anaemia and hyperemia and clearly describes a number of diseases of the blood including lead poisoning, septicemia, and polycytemia." " In the field of hematology the name of Gabriel Andral (1797-1876), a younger colleague of Louis is important. He broke away from the concept of Broussais (1772-1838), the man he succeeded in the Chair of Medicine in Paris, who had championed die ancient belief that most diseases were the result of irritation, especially of the gastrointestinal tract. It was this concept that led Broussais to advocate purging and bloodletting as essential in the treatment of all pathologic conditions and in 1833 resulted in the importation of leeches into France in numbers variously stated as 21 million to 41.5 million in one year. Andral described himself as an eclectic. With his associate, Forget of Strasbourg, he conducted a number of studies on the blood, including its physical and chemical properties and the nature of the process of coagulation, and made use of chemical as well as microscopic procedures. He recognized that anemia could result from food deficiency or loss of blood and gained a wide reputation for his analytical descriptions of clinical problems. His Essai d'Hematologie Pathologique, published in 1845, as stated in Chapter 1, was the first monograph on the subject. After considering die best methods for pursuing studies of pathologic hematology, Andral discussed die blood in plethora, anemia, pyrexias, phlegmasias, hemorrhages, hydropsies, and in "certain diseases commonly called organic," such as cardiac hypertrophy. He paid attention to the fibrin content of die blood and also die quantity of globules and of albumin. Understandably, in the light of present knowledge, many of the views put forward by him are unacceptable; but others were sound. Most important was die fact that he and Forget insisted that there was no need to invoke vitalistic explanations of disease, which even Bichat had favored, and that simple chemical and physical laws sufficed for this purpose. The descriptions of many of the conditions that came to be classified as hematologic disorders, distinguishing them from the confusing mass of ailments that confronted die physicians of earlier times, took root in the 19th century. By this time pathology was developing into a well-defined discipline and clinicians were well versed in this subject, just as pathologists were gready interested in die clinic. Both were aided by progress in histology, which benefited from improvements in microscopy. As examples, Hodgkin's disease, leukemia, and pernicious anemia may be mentioned." Maxwell M. Wintrobe, Heamtology the Blossoming of a Science: A Story of Inspiration and Effort, pp.14-15. Garrison & Morton No.3060; Heirs of Hippocrates 1583

Seller: Antiq. F.-D. Söhn - Medicusbooks.Com, Marburg, Germany